Men with erectile dysfunction (ED) can be treated with the drug Tadalista. It has Tadalafil, an inhibitor of phosphodiesterase type 5 (PDE5), which is comparable to Vardenafil (Levitra) and Sildenafil (Viagra). Tadalista facilitates the development and maintenance of an erection during sexual stimulation by increasing blood flow to the penis. Comparing Tadalafil's effects to those of other ED drugs like Vardenafil and Sildenafil, they last up to 36 hours. This prolonged duration is called the "weekend pill" effect at times.

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